How well can you play guitar? And what a virtual simulation? You can play not only guitar but drums or keyboard. What a great stuff.
For example Guitar Hero is quite fun but Phase Shift is made by fan of this type of game making it even more hardcore, almost simulation. Choose song, more are coming, and press the right keys in the right moment as the marks go by. You can switch from guitar to drums or keys and more. However, what makes the game so great, besides graphics and audio, is the difficulty. The game is hard but so nicely challenging. Of course the best ones will be able to beat the songs on the highest difficulty but for us humans the normal one is fine enough. You can challenge your friends through LAN or online as well.